Stimuli sensitive polymers and self regulated drug delivery systems: A very partial review
نویسندگان
چکیده
منابع مشابه
Temperature and pH stimuli-responsive polymers and their applications in controlled and self- regulated drug delivery
Controlled drug delivery is useful because it allows to obtain better drug product effectiveness, reliability and safety. Interest in stimuli-responsive polymers is steadily gaining increasing momentum especially in the fields of controlled and self-regulated drug delivery. Stimuliresponsive or “smart“ polymers are macromolecules that display a significant physiochemical change in response to s...
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Hydrogels are the 3 dimensional cross linked polymeric networks which absorb the water 10-20 times of its molecular weight. Hydrogels are sensitive to different environmental stimuli like pH, temperature, ion, electric signals, light, pressure, antigen specific, enzyme sensitive, and glucose levels. When the environment is get change they get swell, and swelling is the most important characteri...
متن کاملPolymers and drug delivery systems.
In the treatment of health related dysfunctions, it is desirable that the drug reaches its site of action at a particular concentration and that this therapeutic dose range remains constant over a sufficiently long period of time to alter the process. However, the action of pharmaceutical agents is limited by various factors, including their degradation, their interaction with other cells, and ...
متن کاملStimuli-sensitive protein delivery systems
The development of stimuli-sensitive release systems for protein and peptide delivery has been a subject of significant pharmaceutical importance in recent years, especially in relation to the possible development of intelligent delivery systems. In this review we concentrate on biological and chemical characteristics of these systems and we identify important guidelines as well as unsolved pro...
متن کاملStimuli-responsive polymers and their applications in drug delivery.
Interest in stimuli-responsive polymers is steadily gaining increasing momentum especially in the fields of controlled and self-regulated drug delivery. Delivery systems based on these polymers are developed to closely resemble the normal physiological process of the diseased state ensuring optimum drug release according to the physiological need. Also termed 'environmental-sensitive' or 'smart...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2014
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2014.06.035